Circulating Endothelial Progenitor Cells in Cerebrovascular Disease
نویسندگان
چکیده
منابع مشابه
Circulating Endothelial Progenitor Cells in Cerebrovascular Disease
Stroke is associated with high disability and mortality burdens worldwide, but there are few effective and widely available therapies. There is therefore a need to develop treatments that promote the repair and regeneration of ischemic brain tissue. In this regard, a population of adult stem cells-called endothelial progenitor cells (EPCs)-has been identified in peripheral blood that could prov...
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BACKGROUND AND PURPOSE Endothelial progenitor cells (EPCs) are associated with endothelial repair after ischemia in cardiac or peripheral circulation. There are no reports of EPCs with cerebrovascular disease. We present our experience with EPCs in patients with cerebrovascular disease. SUMMARY OF REPORT EPC counts differed significantly (P<0.001) between stroke patients (acute stroke: median...
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How, then, are we to make progress, when experiments cannot be done in humans, and we cannot trust the results from mice? The answer is, thoughtfully. As Drs Keogh and Menache point out, genes do not work individually or in linear pathways, but rather in networks. We can use mice to work out the links in these networks, while understanding that the relative strengths of the connections are diff...
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OBJECT Recent experimental work suggests that circulating endothelial progenitor cells (cEPCs) are recruited to the angiogenic vascular system of malignant gliomas. Consequently, the level of cEPCs has been proposed as a novel biomarker for the diagnosis and monitoring of these lesions. The aim of the present study was to examine the level of cEPCs and the level of EPC mobilizing mediators in t...
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ژورنال
عنوان ژورنال: Journal of Clinical Neurology
سال: 2008
ISSN: 1738-6586
DOI: 10.3988/jcn.2008.4.4.139